Russian scientists talked about the study of human biological age

Scientists from the Russian Federation have developed calculators that determine the biological age of human organs, as well as identified key markers of aging in order to create a drug that slows down the process. This was announced on December 16 by scientists from three major research universities.

"This allows us to actually diagnose aging and then evaluate the effectiveness of interventions," Olga Tkacheva, director of the Russian Gerontological Research and Clinical Center at the Pirogov Russian National Research Medical University, explained in a conversation with RBC.

The scientist assures that the university has developed calculators for determining the biological age of various organs and systems. This makes it possible to diagnose aging and evaluate the effectiveness of interventions.

In addition, the Pirogov Russian National Research Medical University is investigating brain aging and cognitive decline, as well as the processes of decreasing muscle mass and strength with age. One of the innovations in the fight against this is molecules that destroy "aging cells" — cells that have stopped dividing and accumulated in the body with age.

At the Russian Scientific Center of Surgery named after Academician Petrovsky is developing a "biological age clock" and studying 14 key markers of aging, including muscle strength, walking speed, and changes in DNA. As part of the experiment, geroprotectors, substances that slow down aging, are being tested, said Alexey Moskalev, director of the Institute of Biology of Aging and Medicine of Healthy Longevity. For example, cats were given extracts of green tea and grape seeds, which improved kidney function and activated longevity proteins.

In addition, the MSU Research Institute of Physico-Chemical Biology is investigating the mechanism of autophagy, the process of cell self—purification. With age, this process slows down, which contributes to cell aging, explained Ekaterina Guseva, a junior researcher at the Research Institute. At the current stage, scientists are testing active molecules that prolong the life of nematodes, and plan to conduct research on mice and other animals.

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What new techniques will save the lives and health of many people

Medical Xpress magazine reported on December 12 that lowering blood sugar levels to normal levels can halve the risk of severe cardiovascular disease in people with prediabetes. The return of blood glucose to normal (in fact, remission of prediabetes) reduces the risk of death from cardiovascular diseases or hospitalization for heart failure by more than 50%.

All important news is on the Izvestia channel in the MAX messenger.