Doctors talked about the reasons for weight loss after dieting

People often encounter the fact that the dropped kilograms return after months and years: the biology of the body "pulls" the mass back to its previous values due to hormonal and metabolic adaptation. This was reported by the BBC Science Focus magazine.

"It's not that you did something wrong. The body's task is to return a person to the original mass. For some patients, yo-yo cycles become chronic, and the risk of concomitant diseases with obesity makes the problem a matter of quality and life expectancy," said Fatima Cody Stanford, a physician at Massachusetts General Hospital and a lecturer at Harvard Medical School.

Scientific evidence confirms that dramatic weight loss triggers a long-term "adjustment" of metabolism. It was found that six years after extreme weight loss, people's basal metabolism remained slow and their leptin levels decreased, which increased hunger and increased weight gain.

In parallel, studies point to the role of "adipose tissue memory." Adipocytes retain epigenetic traces of previous obesity even after weight loss, which alters cell function and response to metabolic stimuli, facilitating weight gain when returning to a high-calorie diet. Similar signals were detected in the immune cells of adipose tissue, which can increase inflammation with repeated cycles of mass.

According to the publication, even modern weight loss drugs do not eliminate these "settings" of the body: when patients stop taking GLP-1 agonists, they usually gain some of the lost kilograms, expanded clinical observation data show. Experts emphasize that medications and surgery may be appropriate for individual groups, but a sustainable result requires long—term tactics, from nutrition and sleep correction to moderate physical activity without extreme exertion.

Genetic factors also increase the likelihood of weight gain: inherited variants of hundreds of genes can set a higher "weight range". However, the environment, access to food, stress, and behavioral habits remain a manageable part of the equation.

"It's not a one—time breakthrough that's important, but supported changes," the publication's interlocutors note, advising to avoid "emergency diets" and build a plan together with a doctor, taking into account medical indications and risks.

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On September 1, nutritionist Galina Leonova gave advice on how to calculate calories correctly. To calculate the daily allowance, you can use the Harris—Benedict formula or online calculators. According to the expert, calorie reduction remains the safest way to lose weight, unlike severe starvation. At the same time, it is important to maintain a feeling of fullness and choose high-quality products.

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