Scientists have revealed the effectiveness of vitamin B3 against glioblastoma
Scientists from the University of Calgary in Canada have found that high doses of vitamin B3, also known as niacin, can improve the effectiveness of treatment for glioblastoma, one of the most aggressive and deadly brain tumors. This was reported on June 22 by Science Daily magazine.
What is glioblastoma?
Hotchkiss Brain Institute scientists Gloria Roldan Urgoitti and Wee Yong suggested that niacin is able to restore the work of immune cells that are suppressed by the tumor and help the body fight cancer cells.
Yi Yong, PhD and Professor at the University of Calgary School of Medicine
Normally, the immune system tries to counteract and prevent tumor growth, but this brain cancer suppresses the immune system. Niacin treatment rejuvenates immune cells, allowing them to perform their function of attacking and destroying cancer cells. I see this as an ongoing "battle for the brain."
First, the scientists tested the approach on laboratory mice. The experiments showed an increase in the life expectancy of animals, after which the researchers began a clinical trial of phases I and II with the participation of patients.
The trial evaluates the safety and efficacy of controlled-release niacin in combination with standard radiation and chemotherapy. The interim results were higher than expected. Among the first 24 participants, 82% showed no signs of disease progression six months after starting treatment. This is 28% higher than in previous studies. The authors emphasize that high doses of vitamins can be toxic and should only be used under medical supervision.
On June 19, The Lancet Healthy Longevity magazine reported on the effect of low testosterone levels on an increased risk of cancer death. According to the results of the study, men with a lower concentration of total testosterone in their blood were more likely to die from cancer compared to participants with hormone levels in the upper range.
Переведено сервисом «Яндекс Переводчик»
